CQB News and Events

Upcoming Events & Seminars

Student- & Postdoc-Focused Works-In-Progress Meetings on AI/Automation in Biodesign

Fall 2024 Schedule

 Welcome! Are you a grad student/postdoc looking to share your work to the Center for Quantitative BioDesign community? We would love to hear about your work in progress! Please plan on giving a ~20-minute talk + 10 minutes for Q&A, and we’ll provide pizza and drinks

Preferences to presentation dates will be given on a first come-first serve basis! If you have any questions, please contact Lauren Hong (lauren.hong@duke.edu) or Max Golovsky (maximillian.golovsky@duke.edu).

Date Presenters
Aug 30, 2024 Presenter 1: Tong Chen – (Chatterjee Lab): moPPIt: De Novo Generation of Motif-Specific Binders with Protein Language Models

Presenter 2: Emrah Simsek, PhD – (You Lab): Transfer learning from a protein language model predicts an antibiotic resistance phenotype from genotype

Sept 6, 2024 Presenter 1: Brian Chan – (Rubenstein Lab): Chromatin organization regulated by active loop extrusion

Presenter 2: Hanhyeok Im,PhD – (Venturelli Lab) : Towards an Integrated Computational and Experimental Framework for Deciphering Gene Regulatory Networks in Diverse Bacteria

Sept 20, 2024 Presenter 1: Kinshuk Sahu – (You Lab): Photorealistic P. aeruginosa pattern generation utilizing a deep learning framework

Presenter 2: Lauren Onweller – (Reker Lab): Computationally Guided Design and Synthesis of Self-assembling Combination Therapy Nanoparticles

Oct 11, 2024 Presenter 1: Sophia Vincoff – (Chatterjee Lab): FusOn-pLM: A Fusion Oncoprotein-Specific Language Model via Focused Probabilistic Masking

Presenter 2: Nathaniel Blalock – (Romero Lab): Aligning a Protein Language Model via Reinforcement Learning with Experimental Feedback to Engineer a Brighter Anaerobic Fluorescent Protei

 

Oct 18, 2024 Presenter 1: Rio Watson – (Chatterjee Lab): Degradation of fusion proteins using algorithm-derived peptide-LNP therapeutics leads to mitigation of cancer phenotypes

Presenter 2: Kristen Lok – (You Lab): Colony Morphology Reveals Inoculum Composition of Microbial Communities Using Machine Learning

Nov 15, 2024 Presenter 1: Mary Jia – (Chory Lab): Virus-like particle-assisted directed evolution

Presenter 2: Sri Seshadri – (Romero Lab): Reinforcement Learning with Experimental Feedback (RLXF) for Protein Sequence Optimization

Fall 2024  CQB Seminar Schedule

Time: 3:00 – 4:00 pm

Day of the Week: Friday (s)

Place: Wilkinson Auditorium 021

Date Course Speaker Institution Faculty Host Presentation Title
Sept 27, 2024 seminar Hernan Garcia, Ph.D. UC Berkeley  Lingchong You, PhD. Using Physics as a Microscope to Dissect Transcriptional Dynamics in Development
Oct 4, 2024 seminar Alex Holehouse, Ph.D. Washington University School of Medicine in St. Louis Lucia Strader, Ph.D Mapping from sequence to function in intrinsically disordered regions
Nov 8, 2024 seminar  Theresa Reineke, Ph.D. University of Minnesota Twin Cities Daniel Reker, Ph.D. Macromolecules Optimized via Machine Learning for High Performance Nucleic Acid Delivery
Nov 22, 2024 seminar KC Huang, Ph.D. Stanford University Lingchong You, Ph.D. Predicting the assembly of the gut microbiome
Dec 6, 2024   seminar Jim Pfaendtner, Ph.D.  North Carolina State University Daniel Reker, Ph.D. Using biomimetic polymers to understand and control sequence/structure/function relationships in biomineralization